The core of the Clearbridge BioMedics’ ClearCell™ System lies in the patent-pending microfluidic biochips: The ClearCell™ CTChip®.
The CTChip® encompasses tremendous R&D effort - years of practical experimentation and detailed research on cell shear stress and fluidic characteristics have gone into developing the micro-device capable of separating out Circulating Tumour Cells (CTC) from blood.
Using cutting-edge microfluidics and the differences between biomechanical properties of CTCs and blood cells, the CTChip® contains thousands of crescent-shaped microstructures that can isolate CTCs without the use of antibodies or magnetic beads. As the cells are trapped on the microstructures by the fluid dynamics, reversal of the microfluidic flow allows for cell retrieval.
Clearbridge BioMedics has developed a simple, elegant solution to isolate wholly intact CTCs from patient blood with minimal cell damage.